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How to ensure the content of Lycium barbarum polysaccharide in Goji berry extract?

The active ingredients of Goji berry extract are mainly divided into two categories, Lycium barbarum polysaccharide(LBP), and betaine. The main active ingredient in Goji berry is Lycium barbarum polysaccharide, with a relative molecular weight of 68-200. The immunomodulatory and antitumor effects of Lycium barbarum polysaccharide are the most studied.


In most healthcare foods, there are more than 1,300 approval documents for Goji berry, among which the three main functions are to enhance immunity, anti-fatigue, and relieve visual fatigue, which also matches the main active ingredients of Goji berry extract.


How to effectively eliminate the interference of Goji berry monosaccharides, other plant polysaccharides, and auxiliary materials (maltodextrin, starch, etc.), and reduce the content of LBP in Goji berry extract and Goji berry-related healthcare food?


The relative percentages of glucose, galactose, arabinose, and glucosamine in normal LBP and their adulterated samples were significantly different. Dextrin or dextrin was removed by enzymatic hydrolysis and alcohol precipitation. The interference of soluble starch, complete hydrolysis of LBP, and pre-column PMP derivatization reversed-phase chromatography analysis can realize the detection of doped LBP products and the accurate determination of the actual content of LBP.

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