Helicobacter pylori (Hp) is a common chronic persistent infection in clinics. It is a microaerophilic gram-negative bacteria that can parasitize the surface of the gastric mucosa for a long time by secreting independent factors, leading to gastritis and peptic ulcer, gastric cancer, MAI.T lymphoma, and other diseases.
Clinical medicine has gradually shifted the treatment direction of Hp to bacterial drug therapy with the same source of medicine and food. Studies have found that there are a variety of anti-Hp active substances in bacteria, which are not only reflected in the inhibition and killing of Hp but also can regulate the internal environment of the human body. One of the most classic is the lion's mane, a medicinal and edible fungus that is often used to treat gastrointestinal diseases.
Modern pharmacological studies have shown that the polysaccharides contained in the lion's mane extract can achieve the purpose of eliminating Hp by changing the living environment of Hp; the adenosine and adenine contained in lion's mane have the effect of inhibiting Hp.
The lion's mane extract can reduce the release of lactate dehydrogenase, and has a significant protective effect on the lipid peroxidation of gastric mucosal epithelial cells caused by free radicals generated after Hp infection.