Valerian extract, derived from the root of the valerian plant, has been used for centuries as a natural remedy for various health concerns, particularly for its calming and sleep-aid effects. However, concerns have been raised about the potential negative effects of long-term use of valerian extract on the liver.
Several studies have investigated the impact of valerian extract on liver function, with mixed results. Some animal studies have suggested that high doses of valerian extract may cause liver damage, while others have found no significant adverse effects on liver function. Additionally, there have been a few reported cases of liver injury associated with the use of valerian-containing products in humans, although these instances are rare.
It is important to note that the majority of reported cases of liver injury associated with valerian extract valeric acid involved individuals who were also taking other medications or supplements, making it difficult to attribute the liver damage solely to valerian extract. Furthermore, the specific mechanisms by which valerian extract might potentially cause liver damage are not fully understood.
While the evidence regarding the potential negative effects of long-term use of valerian extract on the liver is inconclusive, it is prudent for individuals considering its use to exercise caution. It is advisable to consult with a healthcare professional before using valerian extract, especially for individuals with pre-existing liver conditions or those taking medications that may interact with valerian extract.